Table 7.
Effect of diets on plasma levels of growth and inflammatory factors
| |
4 wks on diet |
10 wks on diet |
Tumors |
|---|---|---|---|
| |
HFD versus LFD |
HFD versus LFD |
HFD-E versus LFD |
| Serum factor | Fold change | Fold change | Fold change |
| HGF |
- |
- |
2.1 |
| OPG |
1.3 |
- |
- |
| IGF-1 |
1.3 |
- |
- |
| prolactin | - | 0.68 | - |
N = 4 mice on high fat diet (HFD) for 4 wks, n = 4 mice on low fat diet (LFD) for 4 wks; n = 4 mice on HFD for 10 wks, n = 4 mice on LFD for 10 wks; n = 6 HFD mice with early developing tumors (HFD-E), n = 6 LFD mice with tumors. P ≤0.05 for all genes listed.