Table 4.
Multivariate Cox regression analysis of survival
| |
DFS |
OS |
||
|---|---|---|---|---|
|
HR |
P value |
HR |
P value | |
| (95% CI) | (95% CI) | |||
|
DTC status |
|
|
|
|
| Positive versus negative |
1.87 (1.09 to 3.20) |
0.027 |
NS |
|
|
Tumor grade |
|
|
|
|
| Grade III versus Grade II |
NS |
|
3.04 (1.66 to 5.55) |
<0.001 |
|
Nodal status after NACT |
|
|
|
|
| ypN1-3 versus ypN0 |
2.22 (1.18 to 4.19) |
0.014 |
NS |
|
|
Response to NACT |
|
|
|
|
| Nonrespondera versus |
|
|
|
|
| responderb | 2.88 (1.32 to 6.31) | 0.008 | 2.42 (1.04 to 5.64) | 0.041 |
PFS, progression-free survival; OS overall survival; CI, confidence interval; NS, not significant; HR, hazard ratio. aStable or progressive disease; bpCR or partial response.