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Beneficial and detrimental effects of Core Set and ACR20 on trials in rheumatoid arthritis
| Beneficial effects | Detrimental effects |
|---|---|
| Selected outcome measures most likely to change with treatment |
Dichotomized a continuous measures of response |
| Made uniform trial outcome measures across studies, making comparisons possible |
|
| Decreased the number of outcomes from >10 to 7 and then to 1 (ACR20) |
