Table 3.

Definitions of inactive disease and clinical remission in childhood-onset systemic lupus erythematosus

		Medication usage
Construct	Minimal time interval	Corticosteroids	Immunosuppressives	Preventive medicationsa	Medications to treat damage
Inactive diseaseb	Yes	Permissible	Permissible	Permissible	Permissible
Clinical remission on medication	6 months	Permissible	Permissible	Permissible	Permissible
Clinical remission on preventive medication	6 months	No	No	Permissible	Permissible
Clinical remission off medication	12 months	No	No	No	Permissible

^aPreventive medications include systemic medications that can be used to prevent disease damage, such as statins, aspirin, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, bisphosphonates, vitamin D, and omega-3 fatty acids. ^bMedication exposure is not considered.