Table 2.
Correlation of PIK3CA mutation status with clinicopathological parameters
| PIK3CA Mutation (n = 6) | PIK3CA Wild type (n = 51) | P-value | |
|---|---|---|---|
| Age - mean (years) | 62.2 | 63.0 | 0.899 |
| Overall DSS | 33.3% | 33.3% | 1.000 |
| Carrier mutation status | |||
| BRCA1 | 1 | 2 | 0.288 |
| BRCA2 | 0 | 25 | 0.030 |
| BRCAX | 5 | 24 | 0.194 |
| Primary tumour size (mm) | 18.8 | 19.1 | 0.948 |
| Histological type | |||
| Invasive carcinoma - no special type (IC - NST) | 6 | 37 | 0.319 |
| IC-NST with micropapillary areas | 0 | 9 | 0.575 |
| Invasive Papillary Carcinoma | 0 | 3 | 1.000 |
| Invasive Lobular Carcinoma | 0 | 2 | 1.000 |
| Tumour grade | |||
| 1 | 0 | 3 | 1.000 |
| 2 | 3 | 26 | 1.000 |
| 3 | 3 | 22 | 1.000 |
| Lymphovascular invasion | 33.3% | 39.2% | 1.000 |
| Perineural invasion | 50.0% | 41.2% | 0.689 |
| Intrinsic subtype | |||
| Luminal | 6 | 45 | 1.000 |
| HER2 | 0 | 5 | 1.000 |
| Basal | 0 | 1 | 1.000 |
| Null | 0 | 0 | 1.000 |
P-values < 0.05 in bold text.