Table 1.
Demographic and baseline characteristics of 69 localized scleroderma (LS) subjects and 71 healthy control subjects who were included in the plasma analysis
| Characteristics |
LS patients |
Healthy controls |
|---|---|---|
| (number = 69) | (number = 71) | |
| |
number (%) |
number (%) |
| Female |
46 (66.7) |
38 (54) |
| Caucasian |
63 (91) |
unknown |
| |
Median (IQR) |
Median (IQR) |
| Age at plasma sample in years |
12.5 (10.0 to 16.0) |
3 (2.0 to 9.0) |
| Age at disease onset in years |
9 (7.0 to 11.0) |
--- |
| LS subtype |
|
|
| Linear scleroderma trunk/extremity |
26 (37.7) |
--- |
| Linear scleroderma head (En coup de sabre / Parry Romberg Syndrome) |
14 (20.3) |
--- |
| Mixed morphea |
9 (13.0) |
--- |
| Generalized morphea |
8 (11.6) |
--- |
| Plaque (circumscribed superficial) morphea |
5 (7.2) |
--- |
| Deep (circumscribed deep) morphea |
4 (5.8) |
--- |
| Pansclerotic morphea |
1 (1.4) |
--- |
| Clinical measures of activity: |
median (IQR) |
|
| PGA-A |
41.0 (29.0 to 62.0) |
--- |
| mLoSSI | 6.0 (3.0 to 13.0) | --- |
IQR, interquartile range; mLoSSI, modified Localized Scleroderma Skin Score; PGA-A, physician global assessment of activity.