Table 1.
Available samples
| Total accrual | 667 patients | |
|---|---|---|
| Total patients with samples for OPN analyses | ||
| Plasma |
- baseline/4 m |
388 (58%) |
| |
- any time |
624 (94%) |
| Tumor tissue for IHC |
|
462 (69%) |
| Total number plasma samples |
|
2,540 |
| Timing - plasma samples/number of patients | ||
| Baseline (pre-randomization) |
|
314/301 |
| 4 m |
|
374/361 |
| 8 m |
|
396/391 |
| 12 m |
|
406/401 |
| 16 m* |
|
33/29 |
| 24 m |
|
540/487 |
| 36 m |
|
206/159 |
| 48 m* |
|
29/29 |
| 60 m |
|
220/211 |
| Recurrence | 22/20 | |
*later protocol amendment eliminated these sample collections. IHC, immunohistochemistry; OPN, osteopontin.