Table 4.
Univariate Analysis
| Variable | Overall (N = 66) | Benign (N = 28) | Malignant (N = 38) | pa |
|---|---|---|---|---|
| Age (years)b | 57 (22–88) | 49.5 (22–77) | 60 (34–88) | 0.007 |
| Sex | 0.433 | |||
| Male | 32 (48.5) | 12 (42.9) | 20 (52.6) | |
| Female | 34 (51.5) | 16 (57.1) | 18 (47.4) | |
| Cancer history | 0.961 | |||
| Yes | 21 (31.8) | 9 (32.1) | 12 (31.6) | |
| No | 45 (68.2) | 19 (67.9) | 26 (68.4) | |
| Size (mm)b | ||||
| Long-axis | 38 (12–144) | 33.5 (12–74) | 40.5 (15–144) | 0.226 |
| Short-axis | 25 (10–89) | 19.5 (10–56) | 31.0 (12–89) | 0.028 |
| Location | 0.029 | |||
| Left | 33 (50.0) | 12 (42.9) | 21 (55.3) | |
| Right | 18 (27.3) | 5 (17.9) | 13 (34.2) | |
| Midline | 15 (22.7) | 11 (39.3) | 4 (10.5) | |
| Contour | 0.083 | |||
| Smooth | 44 (66.7) | 22 (78.6) | 22 (57.9) | |
| Lobulated | 22 (33.3) | 6 (21.4) | 16 (42.1) | |
| Shape | 0.023 | |||
| Round or ovoid | 58 (87.9) | 21 (75.0) | 37 (97.4) | |
| Thymic shape | 8 (12.1) | 7 (25.0) | 1 (2.6) | |
| Attenuation | 0.892 | |||
| Homogeneous | 36 (54.5) | 15 (53.6) | 21 (55.3) | |
| Heterogeneous | 30 (45.5) | 13 (46.4) | 17 (44.7) | |
| Intralesional fat | 0.002c | |||
| Yes | 7 (10.6) | 7 (25.0) | 0 (0.0) | |
| No | 59 (89.4) | 21 (75.0) | 38 (100.0) | |
| Calcification | 0.417 | |||
| Yes | 5 (7.6) | 3 (10.7) | 2 (5.3) | |
| No | 61 (92.4) | 25 (89.3) | 36 (94.7) | |
| Mediastinal fat infiltration | 0.051 | |||
| Yes | 10 (15.2) | 1 (3.6) | 9 (23.7) | |
| No | 56 (84.8) | 27 (96.4) | 29 (76.3) | |
Data are no. (%), unless otherwise noted.
a
From univariate logistic regression analysis evaluating the association between each patient and lesion feature and lesion status as benign versus malignant, unless otherwise noted.
b
Median (range).
c
Fisher’s exact test.