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. 2013 Oct 22;22(1):178–185. doi: 10.1038/mt.2013.200

Figure 2.

Figure 2

Increased proliferation and metabolic activity in hCPCeβct. (a) CyQuant assay; hCPCeβct exhibited enhanced proliferation compared with hCPCe at 3 and 5 days after catecholamine stimulation (n = 3). (b) Metabolic activity measured by using MTT reagent in hCPCeβct demonstrated improved metabolic activity relative to hCPCe (n = 3). NS, nonsignificant, hCPCe FEN vs. hCPCeβct FEN *P < 0.05, **P < 0.01, ***P < 0.001. hCPCeβct treated with GRK2 inhibitor in the presence of catecholamine stimulation have increased proliferation (c) and metabolic activity (d) compared with hCPCe at day 3 (n = 3). However, there is no significant change in proliferation and metabolic activity between hCPCe and hCPCeβct at 5 days in the presence of GRK2 inhibitor and catecholamine stimulation. hCPCe and hCPCeβct treated with GRK2 inhibitor alone does not show any effect on proliferation and metabolic activity. NS, nonsignificant, hCPCe FEN/inh vs. hCPCeβct FEN/inh *P < 0.05, **P < 0.01, ***P < 0.001. GRK2, G protein-coupled receptor kinase 2; hCPC, human cardiac progenitor cell.