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Ocular biodistribution of SYL040012 in rabbits. Quantification of intact (a,c) SYL040012 and (b,d) 5′-P-SYL040012 in ocular structures. Animals were administered with a single dose of 60 nmol/eye SYL040012 and killed (a,b) 5 and (c,d) 30 minutes after administration. Data represent means ± SEM of three animals per group. AH, aqueous humor; C, cornea; CB, ciliary body; I, iris; LG, lachrymal gland; VH, vitreous humor.
