Table 5.
Linear regression analysis of factors associated with carotid and femoral artery intima-media thickness in systemic sclerosis and systemic lupus erythematosus patients
| Variable |
Mean CCA IMT |
Mean CFA IMT |
||||
|---|---|---|---|---|---|---|
| Standardized beta coefficient | Regression coefficient (95% CI) | P value | Standardized beta coefficient | Regression coefficient (95% CI) | P value | |
|
Systemic sclerosis
a
|
(Constant 0.349; R2 = 50.5%) |
(Constant 0.762; R2 = 49.9%) |
||||
| Age (per year) |
0.664 |
0.007 (0.005 to 0.008) |
<0.001 |
0.336 |
0.004 (0.002 to 0.007) |
0.003 |
| Male sex |
0.202 |
0.088 (0.022 to 0.153) |
0.012 |
0.245 |
0.138 (0.025 to 0.251) |
0.018 |
| Glomerular filtration rate (per unit) |
– |
– |
– |
-0.302 |
-0.003 (0.000 to 0.004) |
0.005 |
| Nicotine use (per pack-year) |
– |
– |
– |
0.198 |
0.002 (0.000 to 0.004) |
0.046 |
|
Systemic lupus erythematosus
b
|
(Constant 0.392; R2 = 52.7%) |
(Constant 0.452; R2 = 31.3%) |
||||
| Age (per year) | 0.726 | 0.006 (0.005 to 0.008) | <0.001 | 0.560 | 0.005 (0.004 to 0.007) | <0.001 |
CCA, common carotid artery; CFA, common femoral artery; CI, confidence interval; IMT, intima-media thickness.
aMultivariate linear regression model for mean CCA IMT and CFA IMT of systemic sclerosis patients. bSimple linear regression model, other additional variables in multivariate analysis did not significantly improve the model for both mean CCA IMT and CFA IMT of systemic lupus erythematosus patients.