Table 1.

Optimised panel of identifying SNPs

Chromosome	Positiona	dbSNP rsID	Gene	Alleles	HapMap 3 AF
					CEU	CHB	JPT	YRI
1	179520506	rs1410592	NPHS2	A/C	0.59	0.62	0.54	0.53
1	67861520	rs2229546	IL12RB2	A/G	0.64	0.36	0.44	0.58
2	169789016	rs497692	ABCB11	A/Gb	0.55	0.65	0.51	0.22
2	227896976	rs10203363	COL4A4	C/T	0.46	0.44	0.36	0.57
3	4403767	rs2819561	SUMF1	A/Gb	0.56	0.73	0.73	0.72
4	5749904	rs4688963	EVC	A/Gb	0.33	0.65	0.67	0.52
5	82834630	rs309557	VCAN	A/Gb	0.49	0.34	0.52	0.50
6	146755140	rs2942	GRM1	C/T	0.54	0.49	0.55	0.47
7	48450157	rs17548783	ABCA13	C/T	0.46	0.72	0.53	0.48
8	94935937	rs4735258	PDP1	C/T	0.40	0.64	0.66	0.46
9	100190780	rs1381532	TDRD7	A/Gb	0.48	0.59	0.50	0.58
10	100219314	rs10883099	HPSE2	A/G	0.52	0.52	0.53	0.62
11	16133413	rs4617548	SOX6	C/T	0.52	0.65	0.61	0.51
12	993930	rs7300444	WNK1	A/G	0.46	0.55	0.48	0.28
13	39433606	rs9532292	FREM2	A/G	0.29	0.41	0.44	0.54
14	50769717	rs2297995	L2HGDH	A/G	0.55	0.65	0.67	0.59
15	34528948	rs4577050	SLC12A6	C/T	0.68	0.75	0.63	0.32
16	70303580	rs2070203	AARS	A/Gb	0.53	0.28	0.51	0.49
17	71197748	rs1037256	COG1	C/T	0.50	0.67	0.65	0.56
18	21413869	rs9962023	LAMA3	A/G	0.67	0.81c	0.75	0.51
19	10267077	rs2228611	DNMT1	C/Tb	0.47	0.73	0.56	0.48
20	6100088	rs10373	FERMT1	G/Tb	0.54	0.31	0.35	0.58
21	44323590	rs4148973	NDUFV3	C/T	0.65	0.33	0.38	0.73
22	21141300	rs4675	SERPIND1	A/C	0.46	0.62	0.51	0.57

^aPosition as defined in genome reference assembly GRCh37 (hg19).

^bSNP is defined on the negative strand.

^cAF marginally outside target range for candidate selection. Selected due to paucity of candidates on chromosome 18.