Table 2.
Comparison of 5HT uptake rate (SUR) in healthy control subjects and patients with chronic HCV.
| N | Mean (SD) | 95% CI (mean) | t-test versus control group | Effect size (d) | 95% CI (d) | |
|---|---|---|---|---|---|---|
| Control group | 65 | 57.3 ( 9.4) | 54.9–59.6 | |||
| Patients total | 65 | 64.8 (15.5) | 61.0–68.7 | t 105.5 = 3.345, P = 0.001 | 0.585 | 0.23–0.93 |
| Patients (BDI ≤ 10) | 49 | 62.5 (14.6) | 58.5–66.9 | t 77.34 = 2.272, P = 0.026 | 0.437 | 0.061–0.812 |
| Patients (BDI > 10) | 16 | 71.3 (17.0) | 62.2–80.4 | t 17.32 = 3.172, P = 0.005 | 1.245 | 0.665–1.825 |
| Patients with major/minor depression | 12 | 80.1 (16.9) | 63.3–90.8 | t 12.3 = 4.545, P = 0.001 | 2.105 | 1.40–2.80 |
Note: the standardized mean-difference effect size (d) was computed from means and standard deviations; SUR is expressed in pMol/109 plts. × 5 min.