Table 2.
Haplotypes of IRF5 used to select polymorphisms.a
| Haplotypeb | % | rs4731530 | rs2402941 | rs6968225 | rs6968508 | rs4728141 | rs729302 | rs2402940 | rs754281 | rs11768806 | rs4728142 | rs1874330 | rs3778754 | rs3757388 | rs3757387 | rs3757385 | rs3807135 | rs2004640 | rs3807307 | rs752637 | rs3823536 | rs3778753 c | rs3807306 | EXON 6 INDEL | rs10954213 | rs13242262 | rs10488630 | rs10488631 | rs2280714 | rs4731535 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | 24.7 | C | G | C | C | C | A | C | C | C | A | T | G | A | C | G | C | T | C | C | A | G | T | A | A | T | G | T | T | T |
| 4 | 1.1 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | G | - | - | - | - | - | - | - |
| 4 | 3.2 | T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| na | 1.6 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | T | - | - | - | - | - | - | - | - | - | - |
| 5 | 3.2 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | A | - | - | - |
| 6 | 6.8 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | G | - | - | A | C | - | C |
| 6 | 2.6 | - | - | - | - | - | - | - | - | - | G | - | - | - | - | - | - | - | - | - | - | - | - | G | - | - | A | C | - | C |
| na | 1.6 | - | - | - | - | T | - | - | - | - | G | - | - | - | T | - | - | - | - | T | - | - | - | - | - | - | A | - | - | - |
| na | 1.6 | T | - | - | - | T | C | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| na | 2.6 | - | - | - | - | T | - | - | - | - | G | - | C | - | T | - | - | - | T | - | G | A | G | G | G | A | A | - | - | C |
| na | 1.1 | - | - | - | - | T | - | - | - | - | G | - | C | - | T | - | - | - | T | T | G | A | G | G | G | A | A | - | - | C |
| 3 | 7.9 | T | A | G | G | T | - | T | T | T | G | C | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 3 | 1.1 | T | A | G | G | T | - | T | - | - | G | - | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 3 | 2.6 | T | - | - | - | - | - | T | T | T | G | C | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 2 | 7.9 | T | - | - | - | T | C | - | - | - | G | - | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 2 | 1.1 | T | - | - | - | T | C | - | - | - | G | - | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 2 | 3.2 | - | - | - | - | T | C | - | - | - | G | - | C | G | T | T | T | G | T | T | G | A | G | G | G | A | A | - | C | C |
| 1 | 5.3 | T | - | - | - | T | C | - | - | - | G | - | C | - | T | - | - | G | T | - | G | A | G | - | - | - | A | - | - | - |
| na | 3.2 | - | - | - | - | T | C | - | - | - | G | - | C | - | T | - | - | G | T | - | G | A | G | - | - | - | - | - | - | - |
| na | 3.2 | T | - | - | - | T | C | - | - | - | G | - | C | G | T | T | T | G | T | T | G | A | - | - | - | - | - | - | - | - |
aDashes represent the same allele as the uppermost sequence. Minor alleles >50% concordant with the C allele of rs729302 are in bold, and the name of the polymorphism is also in bold. IRF5 tag single-nucleotide polymorphisms (SNPs) are in italics. The eight SNPs with high correlation with rs729302 are not represented. bHaplotype numbers are as previously described. na = not applicable for lack of correspondence. cThree completely redundant SNPs