Table 5.
Change in clinical and functional status between baseline and one year by APR levels
| |
Neither APR elevated |
APR levels discordant |
Both APR elevated |
P
value |
|---|---|---|---|---|
| n = 2,520 | n = 1,058 | n = 650 | ||
| mHAQ |
0.01 ± 0.31 |
-0.03 ± 0.40 |
-0.10 ± 0.43 |
<0.0001 |
| CDAI |
-2.40 ± 10.87 |
-3.92 ± 12.37 |
-7.68 ± 14.19 |
<0.0001 |
| Tender joints |
-0.69 ± 5.48 |
-1.28 ± 5.81 |
-2.75 ± 6.98 |
<0.0001 |
| Swollen joints |
-1.12 ± 5.11 |
-1.49 ± 5.53 |
-2.58 ± 5.95 |
<0.0001 |
| Patient global assessment |
-2.38 ± 25.21 |
-4.90 ± 27.78 |
-11.29 ± 30.11 |
<0.0001 |
| MD global assessment | -4.21 ± 17.30 | -6.45 ± 19.78 | -12.57 ± 23.19 | <0.0001 |
APR, acute phase reactant; mHAQ, modified Health Assessment Questionnaire; CDAI, Clinical Disease Activity Index.