Table 1.
Association analysis of rs2544390 with gout
|
Sample set |
Case genotypes, number (frequency) |
Control genotypes, number(frequency) |
Unadjusted |
Adjusted |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CC | CT | TT | T frequency | CC | CT | TT | T frequency | Allelic OR, (95% CI) | P | Allelic OR,(95% CI) | P | |
| European Caucasian |
206(0.371) |
272(0.490) |
77(0.139) |
426 (0.384) |
95(0.337) |
125(0.443) |
62(0.220) |
249 (0.441) |
0.79 (0.64-0.97) |
0.02 |
0.73 (0.52-1.03) |
0.07 |
| Eastern Polynesian |
63(0.168) |
166(0.444) |
145(0.388) |
456 (0.610) |
94(0.176) |
257(0.482) |
182(0.341) |
621 (0.583) |
1.11 (0.92-1.35) |
0.26 |
1.09 (0.82-1.44) |
0.54 |
| Mixed Eastern Western Polynesian |
4(0.191) |
7(0.333) |
10(0.476) |
27 (0.643) |
3(0.167) |
9(0.500) |
6 (0.333) |
21 (0.583) |
1.25 (0.53-2.96) |
0.61 |
9.15 (0.96-87.65) |
0.05 |
| Western Polynesian |
18(0.063) |
129(0.453) |
138(0.484) |
405 (0.711) |
24(0.145) |
66(0.400) |
75(0.455) |
216 (0.655) |
1.30 (0.97-1.75) |
0.08 |
1.21 (0.82-1.77) |
0.33 |
| Ngati Porou Hauora | 25(0.120) | 93(0.447) | 78(0.375) | 249 (0.635) | 38(0.179) | 101(0.476) | 68 (0.321) | 237 (0.572) | 1.30 (0.98-1.73) | 0.07 | 1.25 (0.83-1.88) | 0.29 |
Adjusted against sex, age, body mass index, sugar-sweetened beverage (SSB) consumption (number of drinks/day) and alcohol consumption (g/week). CI, confidence interval; OR, odds ratio.