Table 3.
Incidence of DIC, clinical severity scores, and coagulation parameters at 7 days after administration of Xuebijing injection.
| Control group (n = 83) | Intervention group (n = 88) | P | |
|---|---|---|---|
| DIC (n, %) | 22 (26.51) | 5 (5.68) | <0.001 |
| Platelet (×109/L) | 119.15 ± 91.24 | 131.95 ± 88.36 | 0.205 |
| PT (s) | 21.52 ± 14.81 | 17.2 ± 8 | 0.003 |
| Fibrinogen (g/L) | 3.65 ± 1.63 | 3.67 ± 1.56 | 0.183 |
| D-dimer (mg/L) | 3.72 (1.26–6.37) | 3.45 (1.12–5.87) | 0.743 |
| INR | 1.65 ± 0.83 | 1.65 ± 0.93 | 0.997 |
| MEDS score | 8 (5–18) | 7 (4–15) | 0.039 |
| APACHE II score | 14 (11–27) | 13 (10–25) | 0.107 |
DIC: disseminated intravascular coagulation; MEDS score: Mortality in Emergency Department Sepsis score; APACHE II score: Acute Physiology and Chronic Health Evaluation II score; PT: prothrombin time; INR: international normalized ratio.