Table 3.
HLA-DRB1 alleles classified according to du Montcel et al.
| du Montcel classification | Amino acid sequence positions 70 to 74 | HLA-DRB1 | Patient group % (n) | Controls % (n) | SE | OR | 95% CI | P-value |
|---|---|---|---|---|---|---|---|---|
| S2 | QKRAA | *04:01 | 4.1 (3) | 4.2 (2) | positive | 2.6 | 0.8 to 8.3 | 0.124 |
| DKRAA | *13:03 | |||||||
| S3P | QRRAA | *01:01/02 | 14.9 (11) | 4.2 (2) | ||||
| RRRAA | *10 | |||||||
| S1 | DERAA | *11:02, *13:01/02 | 81.0 (60) | 91.6 (44) | negative | |||
| QARAA | *15 | |||||||
| S3D | DRRAA | *11:01, *12, *16 | ||||||
| X | nonXXRAA | *03,*07,*08,*09,*14 |
[14], in RA patients and controls (homozygous alleles are counted double)
OR, odds ratio; RA, rheumatoid arthritis; SE, shared epitope; A, alanin; D, aspartic acid aspartique; E, glutamic acid; K, leucin; Q, glutamin; R, arginin