Fig. 2.

Schematic illustration of the structural organization of T. brucei SNAREs and representation among the TriRyps. Red ellipses represent the C-terminal SNARE motif, the trans-membrane domain is represented by dark purple rectangles. The Habc domain is represented by green ellipses while the N-terminus longin domain of R-SNAREs is represented by cyan ellipses. Designations are taken from GeneDB accessions. The N-terminus of the protein is drawn towards the left. Dots represent presence (black) or absence (white) from a detectable ortholog in T. brucei, L. major and T. cruzi. A numeral within a circle represents the presence of more than one ortholog. TbR1 is shown spaced from the main body as this SNARE could not be assigned using phylogenetics, but only on BLAST and domain searches.