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Boxplots of serum IL-18 levels (pg/mL) in controls (n = 36), autoantibody negative pSS (n = 18), and autoantibody positive primary Sjögren's syndrome (pSS) (n = 54). Serum IL-18 levels were significantly different between the three groups (P = 0.0003, Kruskal-Wallis test), and highest in autoantibody-positive pSS.
