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. 2012 May 25;153(8):3747–3757. doi: 10.1210/en.2012-1138

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Copyright © 2012 by The Endocrine Society

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Fig. 2. — Endpoint measures at 6 h after MCAO. A, Infarct volumes in PR^+/+ and PR^−/− mice. Two-way ANOVA (PR genotype × brain region) revealed a significant effect of PR genotype (P < 0.001). ***, P < 0.001; **, P < 0.01; *, P < 0.05 as compared with PR^+/+ mice. B, Time spent on a rotarod before or 6 h after MCAO. **, P < 0.01 as compared with preischemia performance; ##, P < 0.01 as indicated. C, Brain levels of progesterone, 5α-DHP, and allopregnanolone in PR^+/+ male mice analyzed by GC/MS (nanograms per gram of tissue). ***, P < 0.001; *, P < 0.05 as compared with control mice (Ctr); ###, P < 0.001; #, P < 0.05 as indicated. Data represent means ± sem; n = 6 per group.