Figure 1.

Example of semi-automated analysis of retinal vessel diameter. (a) SLO image obtained in a subject with papilledema prior to treatment. The black circle displays the location of the OCT RNFL measurement, which was not used in our study. The red circle is the center of the ROI, located 2.25 mm from the optic disc center. The yellow circles are the boundaries of the ROI. The white box outlines a region with a selected inferior vein. (b) Magnified region outlined by white box shown in (a) with inferior vein vessel boundary as identified by the semi-automated image segmentation method indicated by red lines. The white line is a representative vessel cross-section. (c) Normalized intensity profile derived across the cross-section of the inferior retinal vein shown in (b). Width of the profile at half maximum intensity is the measure of vessel width (indicated by double-headed arrow).