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. 2014 Apr 3;55(4):2049–2054. doi: 10.1167/iovs.13-13621

Table.

Comparison of 84 Retinal Vessel Diameter Measurements Made From SLO Fundus Images of Elevated Optic Discs Using Manual and Semi-Automated Analysis Techniques


Interobserver Comparison
Analysis Method Comparison
Manual Analysis
Semi-Automated Analysis
Variability, mean, ±SD (mean, ±) 11 ± 8 μm (10% ± 8%) 3.2 ± 3.5 μm (2% ± 3%)
Pearson's correlation, r 0.90 0.98 0.85
Regression full model
Y-intercept (95% CI) 22.9 μm (−0.3 to 46.0) 7.3 μm (−4.8 to 19.4) 56.3 μm (30.2–82.4)
 Slope (95% CI) 0.79 (0.62–0.96) 0.94 (0.86–1.03) 0.66 (0.46–0.86)
 Vessel-dependent constant (95% CI) −3.9 μm (−40.7 to 33.0) −2.2 μm (−21.5 to 17.1) −5.4 μm (−44.4 to 33.6)
 Vessel-dependent slope (95% CI) −0.06 (−0.40 to 0.28) 0.02 (−0.14 to 0.18) 0.0 (−0.36 to 0.37)
Regression final model
Y-intercept (95% CI) 42.3 μm (28.6–56.0)
 Slope (95% CI) 0.91 (0.81–1.01) 0.95 (0.90–0.99) 0.75 (0.64–0.86)