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. Author manuscript; available in PMC: 2014 Apr 8.
Published in final edited form as: Biol Chem. 2013 Sep;394(9):1205–1212. doi: 10.1515/hsz-2012-0348

Figure 2.

Figure 2

Effect of bradykinin receptor antagonists (A) and cytochrome p450 inhibition (B) on bradykinin relaxations of bovine coronary arteries. Relaxations responses were recorded in arterial rings preconstricted with the thromboxane mimetic U46619 (10 – 50 nM). (A). Arteries were pretreated with the B1 receptor antagonist (B1 antag), des-Arg9[Leu8]bradykinin (1 µM) or the B2 receptor antagonist (B2 antag), D-Arg-0Hyp3-Thi5,8-D-Phe7] bradykinin (1 µM). (B) Arteries were treated with L-NA (30 µM), indomethacin (10 µM) with or without miconazole (10 µM). n = 4–9. Each value represents the mean ± SEM. * significantly different from control.