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Human immune system and liver reconstitution in AFC8-hu mice. (a) PBMCs from humanized mice were stained with 7-AAD (live/dead cell marker) and human and mouse CD45, and the percentage of human immune cell reconstitution in the chimeric mouse was determined. (b) HepPar1 (human hepatocyte)-stained liver tissues from nontransplanted and AFC8 mice transplanted with fetal liver–derived cells. Scale bars, 50 μm.
