Table 1.
MiRNAs that regulate brown adipogenesis
| Name | Species found |
Expression profile |
Role in MYF5 positive cells |
Role in MYF5 negative cells |
Target genes |
REFS |
|---|---|---|---|---|---|---|
| MiR-193b/365 | Mouse Human | BAT, WAT, other | Promotes brown adipogenesis | Promotes white adipogenesis | CDON, IGFBP5, RUNX1t1 | 52 |
| MiR-133a/b | Mouse Human | Muscle, BAT, SAT | Inhibits brown adipogenesis | Inhibits beige adipogenesis | PRDM16 | 63, 65 |
| MiR-196a | Mouse Human | BAT, SAT | No effect | Promotes beige adipogenesis | HOXC8 | 67 |
| MiR-155 | Mouse Human | BAT, WAT | Inhibits brown adipogenesis | Inhibits beige adipogenesis | C/EBPβ | 69 |