Figure 3.

A, nervous tissue can be stretch grown in vitro already interfaced to a commercially available multiple electrode array. On the left, a group of dorsal root ganglion somata are fixed on top of an electrode array. On the right, a group of somata are mechanically displaced, stretch growing the interconnecting axons. B, magnified view of dorsal root ganglion cells located in the proximity of electrodes. After transplantation and integration of this nervous tissue interface with host nerves, efferent activity could be used as commands to drive a prosthetic limb. Likewise, sensory stimuli detected by the prosthetic limb could be transmitted back into the nervous system by stimulating these same neurons with the electrodes.