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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Exp Neurol. 2012 Jan 20;246:35–43. doi: 10.1016/j.expneurol.2012.01.013

Figure 2. Accumulation of Aβ and Associated Proteins in Axonal Bulbs Following TBI in Humans.

Figure 2

(a-c) Double immunofluorescent labeling showing co-accumulation of APP with Aβ in multiple axonal bulbs following TBI. Further immunohistochemical analyses showing co-accumulation of BACE and PS-1 with APP (d–g) and Aβ (h–k) in axonal bulbs. Scale bar: 50 μm.