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. 2014 Feb 10;289(13):8735–8741. doi: 10.1074/jbc.R113.544635

TABLE 1.

H2O2 production rates in intact organ

Isolated hemoglobin-free perfused liver data were obtained by methanol titration of catalase Compound I; from Oshino et al. (9). For discussion, see Refs. 10 and 32.

Substrate or inhibitor H2O2 production rate
nmol of H2O2/min/g of liver wet wt
l-Lactate, 2 mm; pyruvate, 0.3 mm 49
    + Antimycin, 8 μm 75
    + Octanoate, 0.3 mm 170
    + Oleate, 0.1 mm 66
    + Glycolate, 3 mm 490