TABLE 1.
H2O2 production rates in intact organ
Isolated hemoglobin-free perfused liver data were obtained by methanol titration of catalase Compound I; from Oshino et al. (9). For discussion, see Refs. 10 and 32.
Substrate or inhibitor | H2O2 production rate |
---|---|
nmol of H2O2/min/g of liver wet wt | |
l-Lactate, 2 mm; pyruvate, 0.3 mm | 49 |
+ Antimycin, 8 μm | 75 |
+ Octanoate, 0.3 mm | 170 |
+ Oleate, 0.1 mm | 66 |
+ Glycolate, 3 mm | 490 |