TABLE 1.

Overview of structural data used in this work

AU, asymmetric unit.

Structure PDB entry	Protein(s) and organism	Number of subunits in the AU	Detailed description of AU	Detailed co-factors description	Nomenclature of the PII trimer in this paper	Nomenclature of individual effector sites in this paper	Resolution (Å)	Reference
4C3L	PII from	One monomer		None	PIINCI		1.6	This work
	S. elongatus
4C3M	PII from	One trimer		None	PIINCII		2.2	This work
	S. elongatus
4C3K	PII from	Two trimers			PIIADP		3.1	This work
	S. elongatus
			Trimer I	One ADP	PIIADP1	PIIADP1-S1
			Trimer II	Three ADP	PIIADP3	PIIADP3-S1
						PIIADP3-S2
						PIIADP3-S3
2XZW	PII from S. elongatus	Three trimers	Trimer I	Three ATP	PIIOG1	PIIOG1-S1	1.95	(11)
				One Mg2+		PIIOG1-S2
				One 2-OG		PIIOG1-S3
			Trimer II	Three ATP	PIIOG2	PIIOG2-S1
				Two Mg2+		PIIOG2-S2
				Two 2-OG		PIIOG2-S3
			Trimer III	Three ATP	PIIOG3	PIIOG3-S1
				Three Mg2+		PIIOG3-S2
				Three 2-OG		PIIOG3-S3
2XUL	PII from S. elongatus	Two identical trimers		Three ATP	PIIOGex		2.2	(11)
				Three Mg2+
				Three 2-OG
2XBP	PII from S. elongatus (I86N mutant)	One monomer		One ATP			1.2	(9)
				One Mg2+
4AFF	PII from S. elongatus (I86N mutant)	One monomer		One ATP			1.05	(31)
				One Mg2+
				One citrate
1QY7	PII from S. elongatus (S49A mutant)	One trimer		None			2.0	(6)
2J9D	GlnK1 from M. jannashii	Four trimers	Trimer I Trimer II Trimer III Trimer IV	One ADP One AMP One ADP Two ADP			2.1	(42)
1V9O	PII from T. thermophilus	One trimer		Three ADP				(8)
3TA1	PII from A, fulgidus	One trimer		Three ADP			1.9	(30)
3NCR	PII from A. fulgidus	One trimer		Three ADP			1.44	(41)
2XG8	PII/PipX from S. elongatus	One trimeric complex		None			3.2	(24)
3N5B	PII/PipX from Nostoc sp.	One monomeric complex		ADP			1.9	(48)
2V5H	PII/NAGK from S. elongatus	One NAGK hexamer two PII trimers		N-Acetyl-l-glutamate (bound to NAGK)			2.75	(46)