FIGURE 5.

Pleurotolysin also preferentially delivers positively charged proteins. A, cytotoxicity of hGrB delivered into Jurkat cells with either Ply (triangles) or SLO (squares). B, cytotoxicity of cytc delivered into P815 cells with Ply (triangles) or SLO (squares). C, cytotoxicity of N/C-Bid delivered into P185 cells with Ply (triangles) or SLO (squares). D, delivery of eGFP±HS into K562 cell with Ply. FACS data represented as a histogram of eGFP fluorescence where K562 cells treated with Ply alone is in gray, K562 cells treated with eGFP±HS dotted lines, and K562 treated with eGFP±HS in the presence of Ply are represented by solid black lines.