Table 1.

Characteristics of the 75 Research Participants

	Mean (SD) [Range]
	Younger Groups		Older Groups
Characteristic	Carriers (n = 15)	Controls (n = 19)	FXTAS Positive (n = 15)	FXTAS Negative (n = 11)	Controls (n = 15)
Age, y	32.9 (8.1) [20–42]	28.8 (6.9) [18–42]	60.7 (7.7) [50–79]	60.1 (10.6) [47–76]	62.3 (8.1) [52–81]
Educational level, y	15.7 (3.2) [8–21]	14.8 (3.9) [5–20]	14.1 (1.9) [12–18]	15.8 (3.0) [12–20]	15.0 (3.7) [6–20]
FXTAS stage			3.1 (0.7) [2–4]	0.4 (0.5) [0–1]
FMR1 CGG length	95.0 (28.9) [55–157]	28.3 (3.3) [19–31]	102.2 (27.1) [62–154]	80.5 (17.2) [59–113]a	28.2 (5.8) [19–42]
FMR1 mRNA level	3.1 (1.2) [2.2–6.4]	1.5 (0.3) [1.0–1.9]	3.2 (0.9) [2.0–5.6]	2.5 (0.8) [1.4–4.2]	1.5 (0.2) [1.0–2.0]

Abbreviations: FXTAS, fragile X–associated tremor/ataxia syndrome; mRNA, messenger RNA.

^aCompared with the FXTAS-positive group, t = −2.3, P = .03.