Figure 5. Effects of LA and GA on Ca2+ signaling in STC-1 cells.
The studies were performed on STC-1 cells that endogenously express GPR120 but lack CD36 (GPR120+/CD36-), that stably express human CD36 (GPR120+/CD36+) or that express CD36 and are transfected with GPR120 siRNA (GPR120-/CD36+). The changes in intracellular Ca2+ (F340/F380) are shown in response to 5 or 20 μM LA. The data are representative of at 4-5 experiments conducted in triplicates.