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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Contrast Media Mol Imaging. 2014 Jul;9(4):276–282. doi: 10.1002/cmmi.1570

Figure 4.

Figure 4

Retention index of ICG at 20-minute intervals: 20mins (3A), 40mins (3B) and 60mins (3C). The background corrected uptake ratios of ICG in the various light exposure groups were calculated. A) 100J/cm2 was 5-fold and 19.3 fold higher than 30J and 10J/cm2 respectively, while 50J/cm2 was 11.6-fold and 44.4-fold higher respectively. B) 100J/cm2 was 22.2-fold and 43.9-fold higher than 30J and 10J/cm2 respectively, while 50J/cm2 was 16.3-fold and 32.2-fold higher respectively. C) 100J/cm2 was 10.8-fold and 26.1-fold higher than 30J and 10J/cm2 respectively, while 50J/cm2 was 16.4-fold and 39.4 fold higher respectively. At all timepoints, no significant difference was observed between the 2 higher light exposure groups of 100J and 50J/cm2 suggesting that a light dose of 50J/cm2 is optimal for the permeability and retention effect leading to a higher leakage and uptake of ICG into the tumor bed. Key: † - marginally significant, * p<0.05, ** p<0.01