Table S1.
Patient demographics and disease characteristics within five European countries
| Demographics | France
|
Germany
|
UK
|
Italy
|
Spain
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GAD n=1,418 | Non-GAD controls n=1,217 | Mean difference (95% CI) | GAD n=218 | Non-GAD controls n=216 | Mean difference (95% CI) | GAD n=1,055 | Non-GAD control n=1,245 | Mean difference (95% CI) | GAD n=730 | Non-GAD controls n=739 | Mean difference (95% CI) | GAD n=248 | Non-GAD controls n=252 | Mean difference (95% CI) | |
| Mean (SD) age, years | 45.6 (13.2) | 42.4 (12.1) | −3.18 (−4.15, −2.20) | 44.3 (13.1) | 43.7 (12.7) | −0.67 (−3.10, 1.77) | 46.9 (13.5) | 48.8 (13.6) | 1.95 (0.84, 3.06) | 48.7 (13.8) | 47.2 (14.1) | −1.44 (−2.87, −0.02) | 45.7 (13.2) | 44.0 (13.9) | −1.75 (−4.13, 0.63) |
| Male, % | 26.0 | 25.1 | – | 41.7 | 41.7 | – | 38.3 | 38.3 | – | 40.1 | 38.3 | – | 35.5 | 34.5 | – |
| Married, % | 43.1 | 41.7 | – | 33.5 | 43.1 | – | 46.8 | 54.6 | – | 59.2 | 56.2 | – | 52.8 | 49.6 | – |
| Employment status, % | – | – | – | – | |||||||||||
| Employed | 50.9 | 61.6 | – | 45.9 | 49.1 | 48.0 | 56.8 | 65.1 | 65.8 | 68.2 | 57.9 | ||||
| Retired | 16.2 | 2.8 | 18.4 | 14.8 | 17.1 | 13.7 | 18.1 | 13.8 | 11.3 | 11.5 | |||||
| On disability | 6.8 | 7.1 | 7.3 | 5.1 | 16.6 | 14.1 | 0.1 | 0.0 | 3.6 | 4.8 | |||||
| Other | 26.2 | 28.5 | 28.4 | 31.0 | 18.4 | 15.3 | 16.7 | 20.4 | 16.9 | 25.8 | |||||
| Alcohol user, % | 74.3 | 75.8 | – | 71.6 | 77.8 | – | 80.5 | 84.2 | – | 70.1 | 68.3 | – | 64.1 | 73.8 | – |
| Current smoker, % | 39.6 | 35.1 | – | 41.7 | 39.8 | – | 33.7 | 26.2 | – | 34.3 | 27.6 | – | 44.4 | 32.5 | – |
| Mean (SD) days exercised per month | 5.2 (7.6) | 5.5 (7.8) | 0.26 (−0.33, 0.85) | 4.3 (6.6) | 5.3 (7.2) | 1.04 (−0.26, 2.34) | 5.5 (7.7) | 6.0 (8.3) | 0.47 (−0.19, 1.12) | 5.6 (7.6) | 5.3 (7.5) | −0.32 (−1.1, 0.46) | 5.5 (8.0) | 7.4 (8.8) | 1.92 (0.45, 3.40) |
| Comorbidity count | 9.9 (4.4) | 4.3 (3.8) | −5.53 (−5.84, −5.21) | 14.6 (7.9) | 5.5 (4.4) | −9.06 (−10.27, −7.84) | 11.4 (5.0) | 5.8 (4.4) | −5.63 (−6.01, −5.24) | 10.5 (6.3) | 4.6 (4.2) | −5.9 (−6.44, −5.35) | 9.4 (4.7) | 4.2 (3.4) | −5.26 (−5.98, −4.54) |
Note: Control group had no specific GAD diagnosis (self-report) but could have reported another anxiety disorder (eg, social anxiety disorder, panic disorder).
Abbreviations: CI, confidence interval; GAD, generalized anxiety disorder; SD, standard deviation.