Figure 9.

The five different types of Off bipolar cells in the ground squirrel retina are illustrated (above) with a summary of subunit expression (below). The cb1 and cb3 a/b types are pooled (brackets), as we found no differences in their subunit expression patterns. Electrophysiological results represent the consolidation of pharmacological specificity and current–voltage relations. Crossed-out subunits have a low likelihood of contributing to the cone–bipolar cell synaptic response, but are not necessarily absent from the cell. Anatomical results consolidate PCR, in situ hybridization, and immunocytochemistry for the different kainate receptor subunits. AMPA subunits were not investigated, thus this section is not applicable (N/A) to the cb2 cell. GluK4 subunits were excluded based on lack of PCR product in whole retinal isolates.