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A, representative traces of glial ESCs (BGC, first panel) and Purkinje neuron EPSCs (PN, second panel) before (grey trace) and 10 min after (black trace) addition of 3 μm of the N-type Ca2+ channel blocker ω-conotoxin GVIA to the bath. B, concentration–response relationship for glial ESC amplitude (open circles; IC50 = 0.25 μm) and Purkinje neurons EPSC decay time (filled circles; IC50 = 0.28 μm) against conotoxin concentration. Lines are fits to the Hill equation with slope 1.
