Table 1.

Intrinsic membrane properties and responsiveness to substance P in local-circuit neurones (LCNs) and projection neurones (PNs)

	LCNs				PNs
	n	RMP in mV	RIN in GΩ	SP	n	RMP in mV	RIN in GΩ	SP
Total	85	n.a.*	0.97 ± 0.05 (n = 84)	15/41	73	−72.8 ± 0.9 (n = 70)	0.77 ± 0.05 (n = 73)	21/31
Tonic	27	−69.1 ± 1.2 (n = 27)	1.01 ± 0.06 (n = 27)	7/14	53	−72.6 ± 1.1 (n = 51)	0.77 ± 0.06 (n = 53)	18/25
Gap	7	−81.2 ± 2.9 (n = 7)	0.89 ± 0.05 (n = 7)	1/5	2	−82 and −88	0.66 and 1.71	1/2
Rhythmic	40	n.a.*	1.0 ± 0.08† (n = 40)	7/20	0
Burst	0				7	−70.7 ± 1.6 (n = 7)	0.34 ± 0.07 (n = 7)	0/0
Unclassified	11	−62.9 ± 6.4 (n = 6)	0.81 ± 0.26 (n = 10)	0/2	11	−73.0 ± 2.0 (n = 10)	0.94 ± 0.2 (n = 11)	2/4

RMP, resting membrane potential; R_IN, input resistance; n.a., non-applicable.

^*The RMP could not be determined for rhythmic LCNs, and therefore, for the total LCN population.

^†In rhythmic LCNs, sustained hyperpolarizing current was first injected to stop the firing, and then additional hyperpolarizing current pulse was applied to measure R_IN. Unclassified, these neurones showed features typical for more than one group, or changed their firing pattern during recording. SP, substance P; the data for each cell group are presented as the number of responding/tested neurones; pooled data from voltage-and current-clamp experiments.