Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Models, from X-ray crystal structures, of the unliganded open (cyan, PDB entry 5TIM) and the PGH-liganded closed (green, PDB entry 1TRD) forms of TIM from Trypanosoma brucei brucei in the region of the enzyme active site. Reprinted with permission from Ref. 45. Copyright 2011 American Chemical Society.
