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. 2014 Apr 8;9(4):e93129. doi: 10.1371/journal.pone.0093129

Table 3. Factors significantly affecting compliance with clinical guideline recommendations.

Patient or Clinical Characteristic Guideline Recommendation p value
Exercise (n = 195)
Compliant (n = 70) Non-compliant (n = 125)
Age (Median, IQR) 79 (71–84) 82 (75–86) 0.036
Enrolment in heart failure program 33 (47%) 25 (20%) <0.001
IRERs determined 68 (97%) 107 (86%) 0.012
Number of IRERs (Mean ± SD) 24±10 17±11 <0.001
Number of appointments (Median, IQR) 6 (4–11) 3 (2–7) <0.001
Heart failure education (n = 226)
Compliant (n = 170) Non-compliant (n = 56)
Enrolment in heart failure program 73 (43%) 1 (2%) <0.001
IRERs determined 167 (98%) 39 (70%) <0.001
Number of IRERs (Mean ± SD) 24±20 10±9 <0.001
Numbers of appointments (Median, IQR) 5 (3–10) 2 (1–3) <0.001
Management by a cardiologist 48 (28%) 4 (7%) 0.001
Lives alone 54 (32%) 28 (50%) 0.017
Influenza vaccination (n  = 208)
Compliant (n = 170) Non-compliant (n = 38)
Age (Median, IQR) 80 (78–86) 79 (69–84) 0.02
Enrolment in heart failure program 59 (35%) 4 (11%) 0.003
IRERs determined 161 (95%) 27 (71%) <0.001
Number of IRERs (Mean ± SD) 22±10 11±11 <0.001
Numbers of appointments (Median, IQR) 5 (3–10) 2 (1–3) <0.001
Pneumococcal vaccination (n = 183)
Compliant (n = 116) Non-compliant (n = 67)
IRERs determined 108 (93%) 55 (82%) 0.027
Number of IRERs (Mean ± SD) 24±10 17±11 <0.001
Numbers of appointments (Median, IQR) 5 (3–11) 3 (2–5) <0.001
Anticoagulation for AF (n  = 79)
Compliant (n = 69) Non-compliant (n = 10)
Age (Median, IQR) 81 (76–85) 85 (81–94) 0.025
Number of IRERs (Mean ± SD) 20±11 9±9 0.004
Meet HbA1c target in diabetes (n = 114)
Compliant (n = 92) Non-compliant (n = 22)
IRERs determined 90 (98%) 15 (68%) <0.001
Number of IRERs (Mean ± SD) 25±9 17±13 0.011
Numbers of appointments (Median, IQR) 5.5 (3–11) 3 (1–6.3) 0.021
Lipids to target in diabetes (n  = 68)
Compliant (n = 50) Non-compliant (n = 18)
IRERs determined 46 (92%) 13 (72%) 0.048
Number of IRERs (Mean ± SD) 25±11 15±12 0.007
Numbers of appointments (Median, IQR) 6 (2.8–11) 3 (1.8–4.3) 0.028
Blood pressure to target in diabetes (n = 100)
Compliant (n = 91) Non-compliant (n = 9)
IRERs determined 85 (93%) 6 (67%) 0.033
Eye checked in diabetes (n = 69)
Compliant (n = 24) Non-compliant (n = 45)
IRERs determined 24 (100%) 36 (80%) 0.022
Management by a cardiologist 46% 20% 0.03
Lipid lowering therapy in ischemic heart disease (n = 94)
Compliant (n = 81) Non-compliant (n = 13)
Age (Median, IQR) 79 (74.5–83) 83 (79–88.5) 0.014

IRERs, individualised reconciled evidence-based recommendations.