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. 2014 Apr 8;9(4):e93607. doi: 10.1371/journal.pone.0093607

Figure 2. Protein sequences showing inter-species conservation of Keratin-74 and homologies between 26 human type II keratins.

Figure 2

(A) Clustal Omega alignment of part of Keratin-74 shows complete evolutionary conservation of the Phe274 residue (shaded) in all species with a known keratin-74 ortholog. (B) Alignment of parts of the 26 human type II keratins illustrating the almost identical homology at amino-acid position 274 (shaded). Only Keratin-80 deviates by having a biochemically similar leucine at this position. Position of the first amino acid shown is indicated to the left of each protein sequence. KRT: Keratin.