Figure 3. Mouse keratin-74 is expressed in the regenerative nail tissue.

(A) H&E staining of a normal mouse nail unit (40x magnification). The continuous line delineates the border of the nail matrix, the dashed line shows the border of the nail bed, and the dotted line illustrates the hyponychium. nb: nail bed, nm: nail matrix, hn: hyponychium. The boxed section is enlarged in (B). (B) Immunofluorescent staining of keratin-74 shows strong expression in the nail matrix, nail bed and hyponychium (100x magnification). Note the single-cell layer immediately adjacent to the nail plate with pronounced staining. The continuous, dashed and dotted lines correspond to the lines presented in (A).