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. Author manuscript; available in PMC: 2014 Apr 8.
Published in final edited form as: Neuropharmacology. 2012 Apr 4;63(2):322–329. doi: 10.1016/j.neuropharm.2012.03.021

Figure 6.

Figure 6

Penk mRNA levels. Levels of Penk mRNA in CPu (A), NAC core (B) and NAc shell (C) in mice that had cocaine CPP training after withdrawal from escalating-dose binge cocaine or saline administration are shown. Penk mRNA levels in ECocaine-Cocaine group and Saline-Cocaine group are significantly higher than that of the Saline-Saline group in the CPu and NAc core. Penk mRNA levels in the CPu were significantly higher in Ecocaine-cocaine mice with 14 day withdrawal than those with only 1 day withdrawal.