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. 2014 Apr 8;9(4):e93905. doi: 10.1371/journal.pone.0093905

Table 2. List of differentially expressed proteins in plasma of RA patients with respect to healthy control.

Spot No. Protein identified Accession No. M.W.(Da)/PI calculated Peptide matched Biological Functions
1 Haptoglobin beta chain P00738 45,205/6.13 11 Cellular iron ion homeostasis, Defence response to bacterium, Intestinal permeability
2 Human Serum Albumin P02768 69,366/5.92 12 Regulation of the colloidal osmotic pressure of blood, Bile salts transport, Lipid metabolism
3 Serum amyloid protein P02743 26,246/5.97 6 Acute phase inflammation, Transport of cholesterol
4 Apolipoprotein A 1 P02647 30,778/5.56 11 Cholesterol transport, Fat efflux from tissue
5 Alpha-1 Microglobulin P02760 38,999/5.95 9 Cell adhesion, Heme Catabolism, Regulation of Immune response
6 HP alpha 2 chain P00738 16,330/6.1 6 Associated with higher serum iron, Decreased antimicrobial and antioxidant capability, Antigen binding
7 HP alpha 2 chain P00738 16,330/6.1 12 Antigen binding, Defence response
8 HP alpha 2 chain P00738 16,330/6.1 12 Intestinal permeability, allowing intercelllular tight junction disassembly
9 Transthyretin P02766 15,887/5.49 9 Transport, Retinol metabolic process, Phototransduction, extracellulal matrix organization

M.W. – Molecular Weight, PI - Isoelectric Point.