Table 3. Factors Associated with Central Line-Associated Bloodstream Infections: Hospital-wide Prevention Programme for Central Venous Catheter-Associated Bloodstream Infections, University of Geneva Hospitals, 2008–2011.

	Univariable model			Multivariable model
	IRR	95% CI	P-value	IRR	95% CI	P value
Quarter1	0.92	0.88–0.96	<0.001	0.92	0.88–0.96	<.001
Age2	0.99	0.99–1.01	0.772	0.99	0.98–1.01	.301
Gender3	0.91	0.63–1.33	0.637	0.92	0.63–1.35	.658
Charlson comorbidity index4	1.04	0.989–1.11	0.143	1.07	0.99–1.14	.065
ICU stay5	0.82	0.56–1.20	0.298	1.21	0.71–2.07	.475
Multilumen catheters6	1.44	0.87–2.40	0.159	1.47	0.87–2.47	.146
Femoral position7	1.26	0.73–2.19	0.407	1.22	0.69–2.14	.492
Dwell-time (4–6 days)8	2.78	0.80–9.69	0.108	3.12	0.89–10.95	.075
Dwell-time (7–12 days)8	3.53	1.08–11.52	0.037	3.81	1.15–12.63	.029
Dwell-time (>12 days)8	2.97	0.93–9.46	0.066	3.03	0.91–10.09	.070
Placed in the ICU	0.65	0.42–1.01	0.056	0.51	0.29–0.90	.020

ICU: intensive care unit

IRR: incidence rate ratio.

95% CI: 95% confidence interval.

¹Quarter: modelled as per additional quarter.

²Age: modelled as per additional year of age.

³Gender: modelled as male vs. female.

⁴Charlson score: modelled as per score-point increase.

⁵ICU stay: hospitalization in the intensive care unit; modelled as yes vs. no.

⁶Multilumen catheters: any catheter with more than 1 lumen; modelled as yes/no.

⁷Femoral position: any catheter inserted at the femoral site; modelled as yes/no.

⁸Dwell-time (quartiles): 2^nd (4–6 days), 3^rd (7–12 days), and 4^th (>12 days) quartile as compared with the first quartile (1–3 days).