Table 1. Results of an in silico transcription factor binding motif analysis.

Up-regulated genes	Down-regulated genes
GZF1	CHCH
LXR	PPARG
TATA	HIF2A
IRF	ZBTB
ZNF148	ELF ETS
ATF CREB	AP1
TFE	ZFX
GKLF	FKLF
USF	CNOT3
FOX	RNF96
	MYCMAX
	AHRARNTHIF
	E2F

Motives that were enriched in the 1000 bp promoter region upstream of up-regulated lipid related genes are shown on the left, binding motives that were enriched in promoters of down regulated genes on the right and motifs that were associated with up- and down-regulated genes at the bottom. Abbreviations (as used in the Transfac database): AHRARNTHIF: aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator/hypoxia inducible factor, AP1: activator protein 1, AP2: activating protein 2, ATF CREB: activating transcription factor/cAMP response element binding, CHCH: Churchill, CNOT3: CCR4-NOT transcription complex subunit 3, E2F: E2F transcription factor, EGR: early growth response, ELF ETS: E74-like factor/E26 transformation-specific, FKLF: fetal β-like globin gene-activating Krüppel-like factor, FOX: forkhead box, GKLF: gut-enriched Krüppel-like factor, GZF1: GDNF-inducible zinc finger protein 1, HIF2A: hypoxia-inducible factor 2a, IRF: interferon regulatory factor, LXR: liver X receptor, MYCMAX: Myc/Max transcriptional complex, NFY: nuclear factor Y, p53: phosphoprotein p53, PPARG: peroxisome proliferator-activated receptor-gamma, RNF96: RING finger protein 96, SP1SP4: specificity protein 1 and 4, TATA: TATA box, TFE: Transcription Factor E (Family), USF: upstream transcription factor, ZBTB: zinc finger and BTB (broad complex, tramtrack, and bric-à-brac) domain-containing, ZFX: zinc finger X-chromosomal protein, ZNF148: zinc finger protein 148.