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. 2014 Apr 8;9(4):e94122. doi: 10.1371/journal.pone.0094122

Figure 4. Structural comparison of Tv1 teretoxin and M-superfamily conotoxins.

Figure 4

Comparison of the NMR structure of Tv1 with that of M superfamily conotoxins SmIIIA, mr3e, and KIIIA reveals significant structural differences between Tv1 and these conotoxins despite all having the same cysteine scaffold CC-C-C-CC. All structures are shown in cartoon representation with disulfide bonds highlighted in yellow. All figures were prepared using PyMol (www.pymol.org). Conotoxin structural references are as follows: MrIIIe [33] SmIIIA [61] and KIIIA [62].