Figure 2. The increased inflammatory cells in lungs from Bmpr2^delx4+ transgenic mice are primarily in the monocyte lineage.

(A) Number of CD11b cells as a proportion of CD45+ leukocytes in the lung is increased in Rosa26-Bmpr2^delx4+ mice (p<.01 by ANOVA). (B) All categories of CD68 positive circulating cells showed significant increases (* = p<.05), with the increase numerically dominated by interstitial macrophages. (C & D) Some subtypes of alveolar macrophages and dendritic cells also show statistically significant increases (* = p<.05).