Table 2. Analysis of the correlation between differential gene expression (DE) after Zbed6 silencing and the presence of ZBED6 binding sites within 5 kb of the transcription start site (TSS).
| DE genes | ||||
| ZBED6 sites | Non DE genes | All | Up-regulated | Down-regulated |
| Yes | 2681 (24.6%) | 187 (29.8%)a | 131 (32.8%)a | 56 (24.6%) |
| No | 8194 | 440 | 268 | 172 |
| Total | 10875 | 627 | 399 | 228 |
a
Overrepresentation of genes with ZBED6 binding sites among DE genes (Chi square test, two-tailed, d.f. = 1; Non DE genes vs All DE genes, P = 0.004; Non DE genes vs up-regulated DE genes, P = 0.002)